SCHEMBL2379295

SCHEMBL2379295

NC(=O)NCC(O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.48
OR51E2 Q9H255 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
TET2 Q6N021 6/20 0.37
KDM4A O75164 2/20 0.37
KDM4C Q9H3R0 2/20 0.37
KDM2A Q9Y2K7 2/20 0.37
TET3 O43151 2/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
TET1 Q8NFU7 1/20 0.34
GPR84 Q9NQS5 3/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
FFAR1 O14842 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
TGFBR1 P36897 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10197452 0.81 OR51E2 (0.39) BCAT2OR51E2SMN1; SMN2TET2KDM4A
SCHEMBL29222634 0.79 BCAT2 (0.47) BCAT2MEN1KMT2ATDP1CYP2D6
SCHEMBL18125949 0.79 CYP2D6 (0.52) OR51E2SMN1; SMN2TET2KDM4AKDM4C
SCHEMBL538750 0.76
SCHEMBL12461756 0.76 BCAT2 (0.48) BCAT2MEN1KMT2ATDP1CYP2D6
Albizziine SCHEMBL1006299 0.75 GFPT1 (0.48) BCAT2KMT2A
Albizziine SCHEMBL690347 0.75 GFPT1 (0.48) BCAT2KMT2A
Albizziine SCHEMBL9361011 0.75 GFPT1 (0.48) BCAT2KMT2A
Albizziine SCHEMBL1006298 0.75 GFPT1 (0.48) BCAT2KMT2A
Albizziine SCHEMBL439790 0.75 GFPT1 (0.48) BCAT2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080118453-A1 Film-forming solutions comprising vitamin D or derivative thereof and a corticosteroid and dermatological applications thereof GALDERMA S.A. (CH) 2008-05-22 US claimed
EP-1874320-A1 COMPOSITION OF FILM-FORMING SOLUTION TYPE, COMPRISING VITAMIN D OR A DERIVATIVE THEREOF AND A CORTICOSTEROID, AND USE THEREOF IN DERMATOLOGY Galderma S.A. (CH) 2008-01-09 EP claimed
WO-2006111426-A1 COMPOSITION OF FILM-FORMING SOLUTION TYPE, COMPRISING VITAMIN D OR A DERIVATIVE THEREOF AND A CORTICOSTEROID, AND USE THEREOF IN DERMATOLOGY GALDERMA S.A. (CH) 2006-10-26 WO claimed
US-20230374330-A1 CONDUCTIVE ELECTRONIC TEXTILES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2023-11-23 US disclosed
US-20220257545-A1 pH STABLE UREA COMPOSITION AND USE THEREOF Orenova Development Company LLC 2022-08-18 US disclosed
US-20200085764-A1 TOPICAL DELIVERY OF NUCLEIC ACID COMPOUNDS PHIO PHARMACEUTICALS CORP. (US) 2020-03-19 US disclosed
EP-3612152-A1 TOPICAL DELIVERY OF NUCLEIC ACID COMPOUNDS Phio Pharmaceuticals Corp. (US) 2020-02-26 EP disclosed
WO-2018195355-A1 TOPICAL DELIVERY OF NUCLEIC ACID COMPOUNDS RXI PHARMACEUTICALS CORPORATION (US) 2018-10-25 WO disclosed
US-20110218506-A1 AMOROLFINE PATCH FOR THE TREATMENT OF ONYCHOMYCOSIS GALDERMA RESEARCH & DEVELOPMENT (FR) 2011-09-08 US disclosed
US-20100291012-A1 ADMINISTRATION OF AMOROLFINE BY IONTOPHORESIS FOR TREATING NAIL DISEASES GALDERMA S.A. (CH) 2010-11-18 US disclosed
EP-2222307-A1 USE OF AMOROLFINE FOR TREATING A NAIL DISEASE BY IONTOPHORESIS Galderma S.A. (CH) 2010-09-01 EP disclosed
CN-1222923-A Spray-dried polymer compositions and methods thereof CYTEC TECH CORP (US) 1999-07-14 CN disclosed
EP-0906359-A1 SPRAY-DRYING OIL RECOVERY PROCESS Cytec Technology Corp. (US) 1999-04-07 EP disclosed
EP-0906364-A1 WATER-IN-OIL EMULSION SPRAY DRYING PROCESS Cytec Technology Corp. (US) 1999-04-07 EP disclosed
EP-0906358-A2 SPRAY-DRIED POLYMER COMPOSITIONS AND METHODS Cytec Technology Corp. (US) 1999-04-07 EP disclosed
US-5869542-A CONDENSING TO OBTAIN CONDENSED OIL AND CONDENSED WATER; SEPARATION; CONDENSED OIL IS SUBSTANTIALLY FREE OF NON-GASEOUS POLYMERIZATION-DEBILITATING SUBSTANCES; UTILIZES AQUEOUS ACID CYTEC TECHNOLOGY CORP. (US) 1999-02-09 US disclosed
US-5849862-A Processes of spray drying polymer-containing dispersions, water-in-oil emulsions and water-in-oil microemulsions CYTEC TECHNOLOGY CORP. (US) 1998-12-15 US disclosed
WO-1997048755-A1 WATER-IN-OIL EMULSION SPRAY DRYING PROCESS CYTEC TECHNOLOGY CORP. (US) 1997-12-24 WO disclosed
WO-1997048750-A1 SPRAY-DRYING OIL RECOVERY PROCESS CYTEC TECHNOLOGY CORP. (US) 1997-12-24 WO disclosed
WO-1997048732-A2 SPRAY-DRIED POLYMER COMPOSITIONS AND METHODS CYTEC TECHNOLOGY CORP. (US) 1997-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200085764-A1 TOPICAL DELIVERY OF NUCLEIC ACID COMPOUNDS SNRPE, MTREX, NSUN2 BCAT2 4669/4885OR51E2 2378/4885SMN1; SMN2 914/4885
US-20110218506-A1 AMOROLFINE PATCH FOR THE TREATMENT OF ONYCHOMYCOSIS ETF1, SLC7A1, SLC16A1 BCAT2 267/4885OR51E2 232/4885SMN1; SMN2 4847/4885
US-20100291012-A1 ADMINISTRATION OF AMOROLFINE BY IONTOPHORESIS FOR TREATING NAIL DISEASES ETF1, SLC7A1, DPM1 BCAT2 1432/4885OR51E2 1539/4885SMN1; SMN2 3392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.