Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 2/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18118028 | 0.79 | HAO1 (0.55) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9820193 | 0.76 | RAB9A (0.61) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL9820118 | 0.76 | TNIK (0.50) | ROCK1GSK3BMEN1KMT2AMAPT | |
| SCHEMBL13844997 | 0.76 | MAPK10 (0.46) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL834683 | 0.75 | MAPT (0.50) | ROCK1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL23918534 | 0.73 | KDM1A (0.52) | ROCK1ADRA2AADRA2BADRA2CKDM1A | |
| SCHEMBL1272593 | 0.73 | — | — | |
| SCHEMBL20448349 | 0.72 | MEN1 (0.32) | MEN1KMT2AMAPTIDO1HAO1 | |
| SCHEMBL27764418 | 0.71 | AGPAT2 (0.37) | RAB9ANPC1MAPTIDO1HAO1 | |
| SCHEMBL18856847 | 0.70 | ADRA2A (0.44) | ROCK1ADRA2AADRA2BADRA2CKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |