Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794889 | 0.80 | MEN1 (0.64) | RAB9AMAPTNPC1MAPK1MEN1 | |
| SCHEMBL23794887 | 0.79 | RAB9A (0.60) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL23794891 | 0.76 | MAPK10 (0.50) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL23794894 | 0.76 | AURKA (0.49) | RAB9AMAPTGAAALDH1A1HTT | |
| SCHEMBL23794893 | 0.76 | MAPT (0.48) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL23794897 | 0.75 | ROCK1 (0.51) | RAB9AMAPTALDH1A1HTTNPC1 | |
| SCHEMBL5765529 | 0.75 | KMT2A (0.50) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL16290545 | 0.75 | CLK4 (0.54) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL1459772 | 0.73 | MAPT (1.00) | RAB9AMAPTGAAALDH1A1HTT | |
| SCHEMBL39057 | 0.73 | MAPT (1.00) | RAB9AMAPTGAAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |