Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794887 | 0.80 | RAB9A (0.60) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL5788078 | 0.80 | RAB9A (0.43) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL23794893 | 0.80 | MAPT (0.48) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL23794891 | 0.80 | MAPK10 (0.50) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL5765529 | 0.79 | KMT2A (0.50) | AURKARAB9AMEN1KMT2ANPC1 | |
| SCHEMBL23794897 | 0.76 | ROCK1 (0.51) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL23794892 | 0.76 | KMT2A (0.48) | KMT2A | |
| SCHEMBL23794896 | 0.76 | RAB9A (0.59) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL5801454 | 0.70 | CA1 (0.47) | BACE1BACE2 | |
| SCHEMBL306231 | 0.69 | ALDH1A1 (0.57) | AURKARAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |