Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23802375 | 0.86 | FDPS (0.40) | OPRD1OPRK1GPR119FDPSPOLB | |
| SCHEMBL23802374 | 0.84 | OPRD1 (0.37) | OPRD1OPRK1GPR119FDPSPOLB | |
| SCHEMBL4979176 | 0.80 | OPRD1 (0.46) | OPRD1OPRK1GPR119POLBACHE | |
| SCHEMBL25133689 | 0.76 | GPR119 (0.48) | OPRD1OPRK1GPR119POLBNR1H2 | |
| SCHEMBL2731871 | 0.75 | GPR119 (0.45) | OPRD1OPRK1GPR119POLBACHE | |
| SCHEMBL23801901 | 0.75 | NR1H2 (0.44) | GPR119FDPSNR1H2NAMPT | |
| SCHEMBL29021755 | 0.72 | USP2 (0.42) | NR1H2 | |
| SCHEMBL23791324 | 0.71 | FAAH (0.46) | GPR119 | |
| SCHEMBL24362612 | 0.71 | RORC (0.46) | — | |
| SCHEMBL17542155 | 0.71 | NR1H2 (0.44) | GPR119NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210276977-A1 | BICYCLIC INHIBITORS OF HISTONE DEACETYLASE | ALKERMES, INC. | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276977-A1 | BICYCLIC INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC2, HDAC11 | OPRD1 4138/4885OPRK1 4117/4885GPR119 1656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.