Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 18/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 18/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380279 | 1.00 | OPRL1 (0.55) | OPRL1OPRM1OPRK1SLC22A1 | |
| SCHEMBL13650545 | 0.87 | OPRM1 (0.57) | OPRL1OPRM1OPRK1SLC22A1 | |
| SCHEMBL2379490 | 0.86 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3407202 | 0.86 | OPRM1 (0.43) | OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL2379486 | 0.85 | OPRL1 (0.56) | OPRL1OPRM1OPRK1 | |
| SCHEMBL2780290 | 0.83 | OPRL1 (0.59) | OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL2378571 | 0.82 | OPRL1 (0.58) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4702248 | 0.77 | OPRL1 (0.55) | OPRL1OPRM1OPRK1 | |
| SCHEMBL17438529 | 0.77 | OPRM1 (0.41) | OPRL1OPRM1OPRK1SLC22A1 | |
| SCHEMBL14379187 | 0.76 | KDM4E (0.43) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129347-A1 | Cyclohexylacetic acid compounds | ACACA, HCAR2, PCCA | OPRL1 2478/4885OPRM1 3702/4885OPRK1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.