Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAOA | P21397 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | CASP1 | P29466 | 3/20 | 0.57 |
| ▸ | CASP7 | P55210 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506245 | 0.81 | MAOA (0.59) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| SCHEMBL27401495 | 0.81 | MAOA (0.59) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| SCHEMBL20837497 | 0.79 | CYP3A4 (0.50) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| Xanthone SCHEMBL11245548 | 0.77 | MAOA (0.86) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| SCHEMBL4757017 | 0.77 | LMNA (0.61) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| SCHEMBL1180659 | 0.76 | KDM4E (0.62) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| SCHEMBL31566133 | 0.75 | TP53 (0.72) | KDM4ECYP3A4HSD17B10ALDH1A1HPGD | |
| Xanthone SCHEMBL29398266 | 0.74 | MAOA (1.00) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| Xanthone SCHEMBL29358061 | 0.74 | MAOA (1.00) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA | |
| SCHEMBL4696277 | 0.74 | MAOA (0.90) | KDM4ECYP3A4HSD17B10ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284622-A1 | BIOACTIVE POLYMERS WITH ANTI=FOULING PROPERTIES FOR MEDICAL AND DENTAL USES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284622-A1 | BIOACTIVE POLYMERS WITH ANTI=FOULING PROPERTIES FOR MEDICAL AND DENTAL USES | FGB, FIBP, DDOST | KDM4E 3863/4885CYP3A4 4714/4885HSD17B10 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.