Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689460 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MEN1GAAHPGDKMT2A | |
| SCHEMBL23827487 | 0.84 | GAA (0.53) | ALDH1A1MEN1GAAHPGDKMT2A | |
| SCHEMBL23827474 | 0.76 | KMT2A (0.47) | NAPRTALDH1A1MEN1GAAHPGD | |
| SCHEMBL16689456 | 0.75 | GAA (0.43) | ALDH1A1MEN1GAAHPGDKMT2A | |
| SCHEMBL5980806 | 0.75 | IKBKB (0.54) | USP2ALDH1A1MEN1GAAHPGD | |
| SCHEMBL5865211 | 0.74 | ALOX15 (0.56) | USP2ALDH1A1MEN1GAAHPGD | |
| SCHEMBL23827465 | 0.73 | TAAR1 (0.49) | ALDH1A1MEN1GAAHPGDKMT2A | |
| SCHEMBL16689461 | 0.70 | GAA (0.58) | ALDH1A1MEN1GAAHPGDKMT2A | |
| SCHEMBL23827446 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MEN1GAAHPGDKMT2A | |
| SCHEMBL23827442 | 0.70 | ALDH1A1 (0.49) | ALDH1A1MEN1GAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | claimed |