Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23827487 | 0.81 | GAA (0.53) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL5264194 | 0.76 | ALDH1A1 (0.49) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL23827474 | 0.75 | KMT2A (0.47) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL16689456 | 0.75 | GAA (0.43) | TAAR1ALDH1A1GAAMEN1HPGD | |
| SCHEMBL23827461 | 0.73 | TBXAS1 (0.46) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL29021977 | 0.73 | FOLH1 (0.54) | TAAR1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL11163945 | 0.73 | ALOX15 (0.51) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL5865211 | 0.73 | ALOX15 (0.56) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL23827479 | 0.72 | HSD17B10 (0.55) | TAAR1ALDH1A1GAAMEN1HPGD | |
| SCHEMBL11482855 | 0.72 | ALOX15 (0.53) | ALDH1A1GAAMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | claimed |