Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689464 | 0.84 | ALDH1A1 (0.50) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL23827487 | 0.81 | GAA (0.53) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL23827461 | 0.76 | TBXAS1 (0.46) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL23827465 | 0.75 | TAAR1 (0.49) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL5865211 | 0.73 | ALOX15 (0.56) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL23827479 | 0.72 | HSD17B10 (0.55) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL16689456 | 0.71 | GAA (0.43) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL5980806 | 0.71 | IKBKB (0.54) | KMT2AHPGDMEN1ALDH1A1GAA | |
| SCHEMBL28037595 | 0.70 | CYP1A2 (0.51) | ALDH1A1GAASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL23827460 | 0.70 | KMT2A (0.50) | KMT2AHPGDMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | claimed |