Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.45 |
| ▸ | CNR1 | P21554 | 13/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238296 | 0.90 | CNR2 (0.45) | CNR2CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11596103 | 0.82 | MAPT (0.38) | CNR2CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL81552 | 0.81 | S100B (0.53) | MEN1KMT2AL3MBTL1PKMMAPK1 | |
| Oxalic Acid SCHEMBL238206 | 0.79 | S100B (0.45) | CNR2MEN1KMT2AL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL237232 | 0.78 | S100B (0.50) | MEN1KMT2AL3MBTL1PKMMAPK1 | |
| SCHEMBL3229040 | 0.76 | ALDH1A1 (0.65) | CNR2CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10713934 | 0.76 | CNR2 (0.40) | CNR2CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6347837 | 0.73 | CNR2 (0.50) | CNR2CNR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL27885835 | 0.73 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL2440610 | 0.73 | CNR2 (0.50) | CNR2CNR1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2541322-B1 | Composition, process of preparation and method of application and exposure for light imaging paper | INT PAPER CO (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2899592-A1 | Coated substrate comprising a dual wavelength image-forming particulate composition and a process for making said composition | INTERNATIONAL PAPER COMPANY (US) | 2015-07-29 | — | — | EP | disclosed |
| US-20150185608-A1 | IMAGING PARTICULATES, PAPER AND PROCESS, AND IMAGING OF PAPER USING DUAL WAVELENGTH LIGHT | INTERNATIONAL PAPER COMPANY | 2015-07-02 | — | — | US | disclosed |
| US-8980523-B2 | Imaging particulates, paper and process, and imaging of paper using dual wavelength light | INTERNATIONAL PAPER COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| EP-2340463-B1 | IMAGING PARTICULATE COMPOSITION AND IMAGING PROCESS USING DUAL WAVELENGTH LIGHT | INT PAPER CO (US) | 2014-12-17 | — | — | EP | disclosed |
| US-20140080044-A1 | Imaging Particulates, Paper and Process, and Imaging of Paper Using Dual Wavelength Light | INTERNATIONAL PAPER COMAPNY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140080057-A1 | Composition, process of preparation and method of application and exposure for light imaging paper | INTERNATIONAL PAPER COMAPNY (US) | 2014-03-20 | — | — | US | disclosed |
| US-8586279-B2 | Imaging particulates, paper and process, and imaging of paper using dual wavelength light | INTERNATIONAL PAPER COMPANY (US) | 2013-11-19 | — | — | US | disclosed |
| US-8586280-B2 | Composition, process of preparation and method of application and exposure for light imaging paper | INTERNATIONAL PAPER COMPANY (US) | 2013-11-19 | — | — | US | disclosed |
| EP-2541322-A1 | Composition, process of preparation and method of application and exposure for light imaging paper | INTERNATIONAL PAPER COMPANY (US) | 2013-01-02 | — | — | EP | disclosed |
| US-4622286-A | Photoimaging composition containing admixture of leuco dye and 2,4,5-triphenylimidazolyl dimer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0066870-B1 | PHOTOIMAGING COMPOSITIONS CONTAINING SUBSTITUTED CYCLOHEXADIENONE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0024629-B1 | PHOTOIMAGING COMPOSITION COMPRISING A 2,4,5-TRIPHENYLIMIDAZOLYL DIMER AND AT LEAST ONE COMPOUND SELECTED FROM THE GROUP CONSISTING OF A LEUCO DYE AND A POLYMERIZABLE ETHYLENICALLY UNSATURATED MONOMER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-04 | — | — | EP | disclosed |
| EP-0066870-A2 | Photoimaging compositions containing substituted cyclohexadienone compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4341860-A | A P-DI-OR TRICHLOROCYCLOHEXADIENONE OXIDIZER AND A LEUCO DYE OR UNSATURATED MONOMER; PHOTORESISTS; PHOTOPRINTOUT ELEMENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-27 | — | — | US | disclosed |
| EP-0046271-A1 | Photosensitive compositions and elements containing substituted hydroxylamine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| US-4311783-A | Dimers derived from unsymmetrical 2,4,5,-triphenylimidazole compounds as photoinitiators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| US-4298678-A | PHOTOOXIDANT AND LEUCO DYE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0024629-A2 | Photoimaging composition comprising a 2,4,5-triphenylimidazolyl dimer and at least one compound selected from the group consisting of a leuco dye and a polymerizable ethylenically unsaturated monomer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-11 | — | — | EP | disclosed |
| US-4252887-A | HIGH SPEED IMAGING; PHOTOSENSITIVE TO LONGER WAVELENGTHS; USED WITH PHOTOPOLYMERIZABLE OLEFIN; OVERLAY FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |