SCHEMBL23836465

SCHEMBL23836465

CN[C@@H](C[C@@H]1CCNC1=O)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 1/20 0.36
▸ CTSB P07858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25134601 1.00 CTSL (0.36) CTSLCTSB
SCHEMBL25134467 0.91 L3MBTL1 (0.37) CTSLCTSB
SCHEMBL24113137 0.91 L3MBTL1 (0.37) CTSLCTSB
SCHEMBL28732893 0.86 CTSL (0.41) CTSLCTSB
SCHEMBL29613837 0.86 CTSL (0.41) CTSLCTSB
SCHEMBL24020662 0.84 CTSL (0.39) CTSLCTSB
SCHEMBL23824437 0.84 CTSL (0.37) CTSLCTSB
SCHEMBL23824440 0.84 CTSL (0.37) CTSLCTSB
SCHEMBL23824442 0.84 CTSL (0.37) CTSLCTSB
SCHEMBL24108979 0.82 CTSL (0.35) CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312571-A1 RING-MODIFIED PROLINE SHORT PEPTIDE COMPOUND AND USE THEREOF FUJIAN AKEYLINK BIOTECHNOLOGY CO., LTD. (CN) 2023-10-05 — — US disclosed
WO-2023125535-A1 DEUTERATED PEPTIDOMIMETIC COMPOUND AND USE THEREOF 石药集团中奇制药技术(石家庄)有限公司 2023-07-06 — — WO disclosed
US-11351149-B2 Nitrile-containing antiviral compounds PFIZER INC. (US) 2022-06-07 — — US disclosed
WO-2021250648-A1 NITRILE-CONTAINING ANTIVIRAL COMPOUNDS PFIZER INC. (US) 2021-12-16 — — WO disclosed
US-11174231-B1 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2021-11-16 — — US disclosed
US-11124497-B1 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2021-09-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11124497-B1 Inhibitors of cysteine proteases and methods of use thereof CTRL, CTSV, CTSL CTSL 3/4885CTSB 24/4885
US-11174231-B1 Inhibitors of cysteine proteases and methods of use thereof CTRL, CTSV, CTSL CTSL 3/4885CTSB 32/4885
US-20230312571-A1 RING-MODIFIED PROLINE SHORT PEPTIDE COMPOUND AND USE THEREOF VIP, PREP, PRAP1 CTSL 339/4885CTSB 747/4885
US-11351149-B2 Nitrile-containing antiviral compounds ACE2, NOS2, EIF2AK2 CTSL 635/4885CTSB 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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