Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.32 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23837317 | 0.91 | RAB9A (0.34) | HTTKDM4EL3MBTL1THRBTP53 | |
| SCHEMBL17347748 | 0.88 | HTT (0.35) | HTTKDM4EL3MBTL1THRBTP53 | |
| SCHEMBL23130009 | 0.88 | HTT (0.35) | HTTKDM4EL3MBTL1THRBTP53 | |
| SCHEMBL23837304 | 0.82 | TSHR (0.38) | HTTL3MBTL1TP53NPSR1TDP1 | |
| SCHEMBL17347781 | 0.78 | RAB9A (0.36) | HTTKDM4EL3MBTL1THRBTP53 | |
| SCHEMBL23129947 | 0.78 | RAB9A (0.36) | HTTKDM4EL3MBTL1THRBTP53 | |
| SCHEMBL17347697 | 0.77 | MTNR1A (0.36) | HTTKDM4EL3MBTL1THRBTP53 | |
| SCHEMBL23130281 | 0.77 | MTNR1A (0.36) | HTTKDM4EL3MBTL1THRBTP53 | |
| SCHEMBL19663625 | 0.77 | PRKCZ (0.35) | TDP1MEN1ALDH1A1KMT2APRKCZ | |
| SCHEMBL23129955 | 0.76 | CA12 (0.42) | NPSR1TDP1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |