Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23837293 | 0.91 | HTT (0.33) | KDM4EHTTL3MBTL1TP53MAPT | |
| SCHEMBL17347781 | 0.88 | RAB9A (0.36) | RAB9ACYP11B2CYP11B1KDM4EHTT | |
| SCHEMBL23129947 | 0.88 | RAB9A (0.36) | RAB9ACYP11B2CYP11B1KDM4EHTT | |
| SCHEMBL23130281 | 0.80 | MTNR1A (0.36) | RAB9AKDM4EHTTL3MBTL1TP53 | |
| SCHEMBL17347697 | 0.80 | MTNR1A (0.36) | RAB9AKDM4EHTTL3MBTL1TP53 | |
| SCHEMBL23837315 | 0.79 | MTNR1A (0.38) | HTTMAPTMTNR1AMTNR1B | |
| SCHEMBL17347748 | 0.79 | HTT (0.35) | RAB9AKDM4EHTTL3MBTL1TP53 | |
| SCHEMBL23130009 | 0.79 | HTT (0.35) | RAB9AKDM4EHTTL3MBTL1TP53 | |
| SCHEMBL23837505 | 0.78 | MTNR1A (0.32) | CYP11B2CYP11B1MTNR1AMTNR1B | |
| SCHEMBL19663664 | 0.77 | ALDH1A1 (0.34) | RAB9AKDM4EMAPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |