Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 6/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23840305 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2IDH1RIPK1ALDH1A1L3MBTL1 | |
| SCHEMBL23840605 | 0.82 | L3MBTL1 (0.45) | SMN1; SMN2IDH1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL23833441 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2IDH1ALDH1A1TNFNOD2 | |
| SCHEMBL30151089 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2IDH1ALDH1A1TNFNOD2 | |
| SCHEMBL25482866 | 0.80 | L3MBTL1 (0.47) | SMN1; SMN2IDH1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL23840604 | 0.79 | ITGA1 (0.45) | SMN1; SMN2IDH1ALDH1A1MEN1GAA | |
| SCHEMBL23840608 | 0.77 | IDH1 (0.42) | SMN1; SMN2IDH1MEN1MAPTKMT2A | |
| SCHEMBL23840606 | 0.76 | ITGA1 (0.43) | IDH1MEN1GAAMAPTKMT2A | |
| SCHEMBL23840396 | 0.76 | PIK3CD (0.43) | SMN1; SMN2IDH1MEN1GAAMAPT | |
| SCHEMBL23840316 | 0.73 | IDH1 (0.41) | SMN1; SMN2IDH1ALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188907-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |