Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Tributylmethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tributylmethylammonium SCHEMBL93610 | 0.96 | SLC22A1 (0.56) | DNM1SLC22A1HTTSLC22A2 | |
| Tributylmethylammonium SCHEMBL29403115 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HTTSLC22A2 | |
| Tributylmethylammonium SCHEMBL21409548 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HSP90AA1RAD52HTT | |
| Tributylmethylammonium SCHEMBL125277 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HSP90AA1RAD52HTT | |
| Tributylmethylammonium SCHEMBL3321318 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HTTSLC22A2 | |
| Tributylmethylammonium SCHEMBL4617487 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HTTSLC22A2 | |
| Tributylmethylammonium SCHEMBL165919 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HSP90AA1RAD52HTT | |
| Tributylmethylammonium SCHEMBL239485 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HTTSLC22A2 | |
| Tributylmethylammonium SCHEMBL16028454 | 0.93 | SLC22A1 (0.53) | DNM1SLC22A1HTTSLC22A2 | |
| Bromide SCHEMBL5087237 | 0.90 | DNM1 (0.63) | DNM1SLC22A1SMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | ENTEGRIS INC (US) | 2026-01-15 | — | — | US | claimed |
| US-20250381550-A1 | CARBON DISULFIDE TREATED MATERIALS AND METHODS OF PURIFYING FLUIDS USING THE SAME | ZENITH PURIFICATION LLC (US) | 2025-12-18 | — | — | US | claimed |
| EP-4638452-A1 | PROCESS FOR THE PREPARATION OF 7-(4-CHLOROBENZYL)-1-(3-HYDROXYPROPYL)-3-METHYL-8-(3-(TRIFLUOROMETHOXY)-PHENOXY)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | Boehringer Ingelheim International GmbH (DE) | 2025-10-29 | — | — | EP | claimed |
| CN-119976882-A | Method for synthesizing hierarchical pore molecular sieve | 中国石油大学(华东) | 2025-05-13 | — | — | CN | claimed |
| CN-119297397-A | Electrolyte, preparation method thereof and battery | 同济大学 | 2025-01-10 | — | — | CN | claimed |
| US-20240208976-A1 | PROCESS FOR THE PREPARATION OF 7-(4-CHLOROBENZYL)-1-(3-HYDROXYPROPYL)-3-METHYL-8-(3-(TRIFLUOROMETHOXY)-PHENOXY)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-27 | — | — | US | claimed |
| WO-2024133476-A1 | PROCESS FOR THE PREPARATION OF 7-(4-CHLOROBENZYL)-1-(3-HYDROXYPROPYL)-3-METHYL-8-(3-(TRIFLUOROMETHOXY)-PHENOXY)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-27 | — | — | WO | claimed |
| CN-118127539-A | Method for synthesizing triphenyl phosphate by electrocatalytic oxidation of phosphate ions | 南方科技大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117940527-A | Optically clear UV and thermally curable epoxy compositions | 汉高股份有限及两合公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117865789-A | Synthesis method of glutaric acid | 中科合成油技术股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| EP-0666277-A2 | Method for making aromatic polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1995-08-09 | — | — | EP | claimed |
| US-5391692-A | Method for making aromatic polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1995-02-21 | — | — | US | claimed |
| EP-0615857-A1 | Recording sheets containing monoammonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-5320902-A | Suitable for use in ink jet printing | XEROX CORPORATION (US) | 1994-06-14 | — | — | US | claimed |
| EP-0309711-B1 | IMPROVED METHOD FOR THE PREPARATION OF ANILINOFUMARATE | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | claimed |
| US-4814486-A | FOR HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | claimed |
| US-4487722-A | Method of preparing 4-(α-hydrocarbyl-α-cyanomethyl)2,6-di-substituted phenols | ETHYL CORPORATION (US) | 1984-12-11 | — | — | US | claimed |
| EP-0004606-B1 | PROCESS FOR PREPARING ANILINE COMPOUNDS | ETHYL CORPORATION (US) | 1982-03-10 | — | — | EP | claimed |
| US-4186147-A | DISPLACEMENT OF THIOCYANOANILINE WITH AN ALCOHOL TO FORM THIOALKYL ANILINE | ETHYL CORPORATION (US) | 1980-01-29 | — | — | US | claimed |
| EP-0004606-A2 | Process for preparing aniline compounds | ETHYL CORPORATION (US) | 1979-10-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208976-A1 | PROCESS FOR THE PREPARATION OF 7-(4-CHLOROBENZYL)-1-(3-HYDROXYPROPYL)-3-METHYL-8-(3-(TRIFLUOROMETHOXY)-PHENOXY)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE | DPYD, P2RX7, DHPS | DNM1 2170/4885SLC22A1 4403/4885SMN1; SMN2 1973/4885 |
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | TET2, ASIC1, PIEZO1 | DNM1 2538/4885SLC22A1 2747/4885SMN1; SMN2 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.