Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3620179 | 0.74 | NOS3 (0.50) | NNMTALDH1A1 | |
| SCHEMBL23845599 | 0.74 | CHRNB2 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23845626 | 0.74 | NNMT (0.39) | NNMTALDH1A1 | |
| SCHEMBL23833590 | 0.72 | PIK3CB (0.41) | NNMTALDH1A1 | |
| SCHEMBL30094536 | 0.72 | PIK3CB (0.41) | NNMTALDH1A1 | |
| SCHEMBL20772266 | 0.69 | NNMT (0.37) | NNMTALDH1A1 | |
| SCHEMBL20772252 | 0.69 | NNMT (0.37) | NNMTALDH1A1MDM2 | |
| SCHEMBL24099889 | 0.69 | ALDH1A1 (0.42) | NNMTALDH1A1MDM2 | |
| SCHEMBL4751919 | 0.69 | NNMT (0.37) | NNMTALDH1A1 | |
| SCHEMBL23029357 | 0.67 | NNMT (0.32) | NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188938-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | AKEBIA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |