Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932287 | 0.58 | ALDH1A1 (0.33) | KDM4EALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL7802796 | 0.56 | KMT2A (0.40) | KDM4EALDH1A1HPGDHTTNCOA1 | |
| SCHEMBL23644930 | 0.56 | LGMN (0.50) | LGMNKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6299915 | 0.56 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1MPOXDHRXFP1 | |
| SCHEMBL7544529 | 0.56 | LGMN (0.37) | LGMNKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL516430 | 0.55 | PDE2A (0.44) | LGMNKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL18633341 | 0.52 | CYP19A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL23777294 | 0.51 | KDM4E (0.38) | LGMNKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6048397 | 0.51 | NPC1 (0.38) | LGMNKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL23635688 | 0.51 | KDM1A (0.41) | LGMNKDM4EALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2553019-A1 | MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF | Mersana Therapeutics, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120053-A1 | MODIFIED POLYMERS FOR DELIVERY OF POLYNUCLEOTIDES, METHOD OF MANUFACTURE, AND METHODS OF USE THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2011-09-29 | — | — | WO | disclosed |