SCHEMBL6048397

SCHEMBL6048397

Cn1c(=S)[nH]cc(N)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.35
▸ LGMN Q99538 1/20 0.32
▸ CASP6 P55212 1/20 0.32
▸ ATAD2 Q6PL18 2/20 0.32
▸ LMNA P02545 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ LPO P22079 1/20 0.31
▸ PTGS1 P23219 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ PIK3CD O00329 1/20 0.31
▸ ALPL P05186 1/20 0.31
▸ ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11480635 0.78 ADORA2A (0.36) CASP6ATAD2LMNAALDH1A1CYP1A2
SCHEMBL9679900 0.77 MPO (0.41) TDP1KDM4EALDH1A1
SCHEMBL11304106 0.68 NPC1 (0.56) NPC1ALOX12RAB9ATDP1KDM4E
SCHEMBL427428 0.68 NPC1 (0.33) NPC1ALOX12RAB9ATDP1KDM4E
SCHEMBL9770361 0.66 — —
SCHEMBL10865950 0.64 — —
SCHEMBL4146947 0.64 CASP6 (0.41) KDM4ECASP6ATAD2ALDH1A1LPO
SCHEMBL15804043 0.62 ATAD2 (0.38) TDP1KDM4EATAD2MEN1ALDH1A1
SCHEMBL28143899 0.61 LGMN (0.39) ALOX12TDP1KDM4ELGMNCASP6
SCHEMBL28459507 0.61 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106170553-A Modified nucleic acid molecules and uses thereof 现代治疗公司 2016-11-30 — — CN claimed
CN-110520409-A Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX INC 2019-11-29 — — CN disclosed
CN-110506119-A The design of AAV capsid UNIV MASSACHUSETTS 2019-11-26 — — CN disclosed
CN-110456035-A Probing analysis and its application based on cell BERG LLC 2019-11-15 — — CN disclosed
CN-110177544-A Exosomes for delivering therapeutic agents 普尔泰克健康有限公司 2019-08-27 — — CN disclosed
CN-110042099-A RNA in skin and fibrotic conditions is interfered 菲奥医药公司 2019-07-23 — — CN disclosed
CN-106471133-B Mononucleotide detection method 贝斯4创新公司 2019-07-09 — — CN disclosed
CN-105378109-B Minimizing errors using uracil-DNA-N-glycosylase 雅培分子公司 2019-06-14 — — CN disclosed
CN-109563509-A Target the delivering nucleic acid compound certainly of the reduction size of long non-coding RNA 阿克赛医药公司 2019-04-02 — — CN disclosed
CN-105131067-B RNA in skin and fibrotic conditions is interfered 雷克西制药公司 2019-02-19 — — CN disclosed
CN-1537166-A New elongase gene and production of Delta 9-polyunsaturated fatty acids ����˹�ж���ѧ 2004-10-13 — — CN disclosed
CN-1531440-A Pharmaceutical composition for preventing or treating Th1 and Th2 cell-related diseases by regulating Th1/Th2 ratio - 2004-09-22 — — CN disclosed
CN-1526025-A Genes expressed in breast cancer as prognostic and therapeutic targets ��˹��ŵ�� 2004-09-01 — — CN disclosed
CN-1498271-A Potassium channel interactors protein and uses therefor ǧ��ҩƷ��˾ 2004-05-19 — — CN disclosed
CN-1451047-A Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins BASF AG (DE) 2003-10-22 — — CN disclosed
CN-1430505-A Microspheres for active embolization BIOSPHERE MEDICAL INC (US) 2003-07-16 — — CN disclosed
CN-1429277-A Method for detecting difference between nucleic acids FRESHGENE INC (US) 2003-07-09 — — CN disclosed
CN-1426307-A Protein OXFORD GLYCOSCIENCES UK LTD (GB) 2003-06-25 — — CN disclosed
CN-1346368-A Potassium channel interactors and uses therefor MILLENNIUM PHARM INC (US) 2002-04-24 — — CN disclosed
CN-1312372-A Intocostrin regulation area and nucleotide series determination and method used thereof PFIZER PRODUCTS CORP (US) 2001-09-12 — — CN disclosed
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