SCHEMBL23851345

SCHEMBL23851345

C#CC1(NC(=O)C(F)(F)F)CC1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CA2 P00918 1/20 0.36
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2106914 0.79 CTSC (0.42)
SCHEMBL24814613 0.75 DGAT1 (0.50) POLBMEN1KMT2A
SCHEMBL14893926 0.73
SCHEMBL12666587 0.71 MEN1 (0.59) POLBMEN1KMT2A
SCHEMBL25755229 0.67 CA2 (0.40) POLBMEN1KMT2ACA2ALDH1A1
SCHEMBL14904840 0.67 CTSL (0.43) POLBMEN1KMT2ACA2
SCHEMBL2722431 0.65 CA2 (0.39) POLBMEN1KMT2ACA2ALDH1A1
SCHEMBL21177433 0.65 MEN1 (0.58) POLBMEN1KMT2A
Hydrochloric Acid SCHEMBL5568383 0.65 CTSS (0.36)
SCHEMBL23957778 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220002279-A1 NOVEL IMIDAZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2022-01-06 US disclosed
US-20220002279-A1 NOVEL IMIDAZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2022-01-06 US disclosed
EP-3884940-A1 NOVEL IMIDAZOLE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2021-09-29 EP disclosed
EP-3884940-A1 NOVEL IMIDAZOLE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2021-09-29 EP disclosed
CN-112996505-A Novel imidazole derivatives 大正制药株式会社 2021-06-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002279-A1 NOVEL IMIDAZOLE DERIVATIVE SLC11A2, MLX, LPXN POLB 3819/4885MEN1 3530/4885KMT2A 226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.