SCHEMBL2385142

SCHEMBL2385142

CCCCCCCCCCc1ccccc1C(=O)OCCCCCC

nearest known ligand 0.77

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.77
TSHR P16473 5/20 0.77
LMNA P02545 3/20 0.77
MAPK1 P28482 3/20 0.73
CYP3A4 P08684 2/20 0.73
TP53 P04637 1/20 0.73
KDM4E B2RXH2 3/20 0.67
HSD17B10 Q99714 2/20 0.67
POLB P06746 1/20 0.67
L3MBTL1 Q9Y468 3/20 0.66
TDP1 Q9NUW8 2/20 0.66
SCN1A P35498 2/20 0.55
SCN2A Q99250 2/20 0.55
SCN3A Q9NY46 2/20 0.55
MAPT P10636 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147852 1.00 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL28239832 1.00 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL451075 1.00 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL2385137 1.00 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL21800979 1.00 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL5407185 0.97 ALDH1A1 (0.71) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL28106513 0.97 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL5407181 0.97 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL27975029 0.97 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL28149248 0.97 ALDH1A1 (0.77) ALDH1A1TSHRLMNAMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107526256-B Toner compositions with anti-plasticizers 施乐公司 2023-04-07 CN disclosed
US-8394394-B2 Mousse formulations L'ORÉAL (FR) 2013-03-12 US disclosed
CN-101460146-B Vesicular formulations containing organic acid prodrugs and process for their preparation UNIV LISBOA 2013-01-09 CN disclosed
US-20120301415-A1 COMPOSITIONS HAVING ENHANCED COSMETIC PROPERTIES L'OREAL (FR) 2012-11-29 US disclosed
US-8025869-B2 Cosmetic compositions having enhanced wear properties L'ORÉAL (FR) 2011-09-27 US disclosed
CN-101917958-A Powder cosmetic composition AVON PROD INC 2010-12-15 CN disclosed
US-7262158-B1 Cleansing compositions comprising a liquid silicone and ester mixture JOHNSON & JOHNSON COMPANIES, INC. (US) 2007-08-28 US disclosed
US-20070093619-A1 Compositions having enhanced cosmetic properties L'OREAL (FR) 2007-04-26 US disclosed
EP-1758547-A1 COSMETIC MOUSSE FORMULATIONS L'OREAL (FR) 2007-03-07 EP disclosed
US-20060292106-A1 Shaving preparation L'OREAL (FR) 2006-12-28 US disclosed
CN-1385457-A Gel composition PANRICO PARTNERSHIP INC (US) 2002-12-18 CN disclosed
EP-1216685-A2 Personal care compositions Johnson & Johnson Consumer Companies, Inc. (US) 2002-06-26 EP disclosed
CN-1348815-A Medicine for preventing and treating coronary heart disease and angina pectoris and its prepn and other use TIANJIN TIANSHILI PHARMACEUTIC (CN) 2002-05-15 CN disclosed
US-20020035046-A1 Personal care compositions JOHNSON & JOHNSON CONSUMER INC. 2002-03-21 US disclosed
WO-2001001949-A9 CLEANSING COMPOSITIONS JOHNSON & JOHNSON CONSUMER (US) 2001-03-22 WO disclosed
WO-2001001949-A1 CLEANSING COMPOSITIONS JOHNSON AND JOHNSON CONSUMER COMPANIES, INC. (US) 2001-01-11 WO disclosed
EP-0988019-A1 COSMETIC COMPOSITIONS CONTAINING SMECTITE GELS AVON PRODUCTS, INC. (US) 2000-03-29 EP disclosed
WO-1999065455-A1 GEL MATRIX NON-EMULSION COMPOSITION CONTAINING TWO CLAY GELS AVON PRODUCTS, INC. (US) 1999-12-23 WO disclosed
US-5882662-A COSMETICS WITH SMECTITE CLAY AND POLAR SOLVENTS AVON PRODUCTS, INC. (US) 1999-03-16 US disclosed
WO-1998050003-A1 COSMETIC COMPOSITIONS CONTAINING SMECTITE GELS AVON PRODUCTS, INC. (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035046-A1 Personal care compositions CUTA, DSG1, KRT18 ALDH1A1 2534/4885TSHR 4229/4885LMNA 1546/4885
US-20120301415-A1 COMPOSITIONS HAVING ENHANCED COSMETIC PROPERTIES RARA, CUTA, RXRA ALDH1A1 1513/4885TSHR 2932/4885LMNA 1235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.