Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.50 |
| ▸ | MGLL | Q99685 | 6/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL16970580 | 0.95 | MGLL (0.53) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6991874 | 0.93 | PTGS1 (0.56) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL4971470 | 0.93 | PTGS1 (0.56) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL247137 | 0.89 | PTGS1 (0.44) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL4967709 | 0.87 | MGLL (0.47) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL1047471 | 0.83 | MGLL (0.71) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL30433783 | 0.82 | PTGS1 (0.63) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Hydrochloric Acid SCHEMBL16876819 | 0.81 | MGLL (0.68) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL3420976 | 0.81 | MGLL (0.56) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL3420580 | 0.80 | PTGS1 (0.47) | PTGS1PTGS2MGLLFAAHHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12048710-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-30 | — | — | US | disclosed |
| EP-4045088-A1 | METHOD FOR THE PREPARATION OF POLYMERIC CARRIERS FOR PH- CONTROLLED DRUG RELEASE AND THEIR CONJUGATES WITH DRUGS | Ustav Makromolekularni Chemie AV CR, v.v.i. (CZ) | 2022-08-24 | — | — | EP | disclosed |
| US-20220202837-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-30 | — | — | US | disclosed |
| US-11278554-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-22 | — | — | US | disclosed |
| US-20220054658-A1 | CONJUGATES | TRANSFECTION HOLDINGS LIMITED (NZ) | 2022-02-24 | — | — | US | disclosed |
| CN-113474007-A | Conjugates | 特兰斯丰特控股有限公司 | 2021-10-01 | — | — | CN | disclosed |
| US-20200046742-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-02-13 | — | — | US | disclosed |
| US-10434111-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-08 | — | — | US | disclosed |
| US-10308679-B2 | Soluble intein fusion proteins and methods for purifying biomolecules | MERCK PATENT GMBH (DE) | 2019-06-04 | — | — | US | disclosed |
| US-20170291919-A1 | Soluble Intein Fusion Proteins And Methods For Purifying Biomolecules | EMD MILLIPORE CORPORATION | 2017-10-12 | — | — | US | disclosed |
| EP-1812031-B1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | UNIV CALIFORNIA (US) | 2015-06-24 | — | — | EP | disclosed |
| US-20130344527-A1 | Compositions and Methods for Modification of Biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-26 | — | — | US | disclosed |
| US-8461298-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-11 | — | — | US | disclosed |
| US-8431558-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-30 | — | — | US | disclosed |
| US-20110213123-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-09-01 | — | — | US | disclosed |
| US-7807619-B2 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090068738-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-03-12 | — | — | US | disclosed |
| EP-1812031-A2 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-01 | — | — | EP | disclosed |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-05-25 | — | — | US | disclosed |
| WO-2006050262-A2 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12048710-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-20220202837-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-20130344527-A1 | Compositions and Methods for Modification of Biomolecules | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-10434111-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-20090068738-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-11278554-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-20110213123-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-20220054658-A1 | CONJUGATES | RTN3, RER1, HRH4 | PTGS1 3391/4885PTGS2 3478/4885MGLL 2455/4885 |
| US-20200046742-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | PTGS1 2564/4885PTGS2 2726/4885MGLL 2030/4885 |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | PTMS, QPCT, DNPEP | PTGS1 2434/4885PTGS2 2792/4885MGLL 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.