Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | MGLL | Q99685 | 6/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4971470 | 1.00 | PTGS1 (0.56) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL16970580 | 0.98 | MGLL (0.53) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL2385691 | 0.93 | PTGS1 (0.50) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL247137 | 0.86 | PTGS1 (0.44) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL30433783 | 0.86 | PTGS1 (0.63) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL338631 | 0.84 | MGLL (0.77) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL4174559 | 0.84 | MGLL (0.77) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL9999878 | 0.84 | MGLL (0.77) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL25586313 | 0.84 | MGLL (0.77) | PTGS1PTGS2MGLLFAAHHSP90AA1 | |
| SCHEMBL25586311 | 0.84 | MGLL (0.77) | PTGS1PTGS2MGLLFAAHHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330249-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| EP-4185328-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF | Genentech, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-20220054658-A1 | CONJUGATES | TRANSFECTION HOLDINGS LIMITED (NZ) | 2022-02-24 | — | — | US | disclosed |
| WO-2022020288-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF | GENENTECH, INC. (US) | 2022-01-27 | — | — | WO | disclosed |
| EP-0966458-B1 | SULFONATED XANTHENE DERIVATIVES | MOLECULAR PROBES INC (US) | 2003-08-13 | — | — | EP | disclosed |
| EP-1090073-B1 | XANTHENE DYES AND THEIR APPLICATION AS LUMINESCENCE QUENCHING COMPOUNDS | MOLECULAR PROBES INC (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6399392-B1 | LUMINESCENCE CORRELATES TO SEPARATION DISTANCE | MOLECULAR PROBES, INC. | 2002-06-04 | — | — | US | disclosed |
| US-6130101-A | FLUORESCENT PROBES FOR USE IN BIOLOGICAL SAMPLES | MOLECULAR PROBES, INC. (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0966458-A1 | SULFONATED XANTHENE DERIVATIVES | Molecular Probes Inc. (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999015517-A1 | SULFONATED XANTHENE DERIVATIVES | MOLECULAR PROBES, INC. (US) | 1999-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330249-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF | ADRM1, CD79B, BRDT | PTGS1 3115/4885PTGS2 3186/4885MGLL 2530/4885 |
| US-20220054658-A1 | CONJUGATES | RTN3, RER1, HRH4 | PTGS1 3391/4885PTGS2 3478/4885MGLL 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.