Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864366 | 0.85 | MAPT (0.37) | HPGDALDH1A1KMT2A | |
| SCHEMBL23864280 | 0.81 | PYGL (0.53) | HPGDKDM4EALDH1A1PYGLPTGER4 | |
| SCHEMBL23864722 | 0.80 | ALDH1A1 (0.40) | PLA2G1BATG4BTP53HPGDKDM4E | |
| SCHEMBL23864723 | 0.80 | MAPT (0.37) | HPGDALDH1A1LMNAKMT2A | |
| SCHEMBL23864370 | 0.76 | LMNA (0.35) | HPGDKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL23864263 | 0.76 | LMNA (0.35) | HPGDKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL23864637 | 0.72 | TXNRD1 (0.37) | HPGDALDH1A1LMNAKMT2A | |
| SCHEMBL24006700 | 0.72 | HRH4 (0.30) | — | |
| SCHEMBL23864209 | 0.70 | PTGER4 (0.51) | TP53ALDH1A1PYGLPTGER4PTGER2 | |
| SCHEMBL21207989 | 0.70 | CES2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |