Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864490 | 0.91 | KMT2A (0.36) | SMN1; SMN2KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL23864435 | 0.83 | KMT2A (0.38) | SMN1; SMN2KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL23864341 | 0.82 | KMT2A (0.40) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL23864722 | 0.76 | ALDH1A1 (0.40) | KMT2AHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL19415763 | 0.71 | TRPA1 (0.42) | SMN1; SMN2NPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL24529103 | 0.71 | ALDH1A1 (0.49) | SMN1; SMN2KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL13369666 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2ANPC1HPGDALDH1A1 | |
| SCHEMBL23864723 | 0.70 | MAPT (0.37) | KMT2AHPGDALDH1A1MAPTLMNA | |
| SCHEMBL23864208 | 0.69 | HPGD (0.32) | KMT2AHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1363368 | 0.68 | TRPA1 (0.42) | SMN1; SMN2KMT2ANPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |