Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864490 | 0.91 | KMT2A (0.36) | KMT2AHDAC1HDAC6NR1H4EPHX2 | |
| SCHEMBL23864435 | 0.88 | KMT2A (0.38) | KMT2AHDAC1HDAC6NR1H4EPHX2 | |
| SCHEMBL23864571 | 0.82 | SMN1; SMN2 (0.39) | KMT2AALDH1A1MAPTRAB9ATP53 | |
| SCHEMBL23864722 | 0.76 | ALDH1A1 (0.40) | KMT2AALDH1A1TP53HTTKDM4E | |
| SCHEMBL21900873 | 0.74 | HSD17B1 (0.46) | KMT2AALDH1A1MAPTRAB9ATP53 | |
| SCHEMBL12339916 | 0.70 | ALDH1A1 (0.48) | KMT2AALDH1A1RAB9AKLKB1KDM4E | |
| SCHEMBL23864280 | 0.69 | PYGL (0.53) | KMT2ANR1H4EPHX2ALDH1A1KDM4E | |
| SCHEMBL1362104 | 0.69 | ALDH1A1 (0.54) | KMT2AALDH1A1TP53TDP1PLK1 | |
| SCHEMBL26803751 | 0.69 | IKBKB (0.42) | ALDH1A1MAPTKLKB1KDM4E | |
| SCHEMBL23864209 | 0.68 | PTGER4 (0.51) | KMT2ANR1H4EPHX2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |