Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19540906 | 0.85 | SIRT2 (0.52) | SIRT2KDM4EALDH1A1LMNASLC7A5 | |
| SCHEMBL5262346 | 0.84 | SIRT2 (0.49) | SIRT2KDM4EALDH1A1LMNASLC7A5 | |
| SCHEMBL17683316 | 0.83 | SIRT2 (0.50) | SIRT2CYP4F2CYP4A11TLR7 | |
| SCHEMBL12255149 | 0.82 | SIRT2 (0.52) | SIRT2KDM4EALDH1A1LMNASLC7A5 | |
| SCHEMBL28655132 | 0.82 | SLC7A5 (0.57) | SIRT2KDM4EALDH1A1LMNASLC7A5 | |
| SCHEMBL1410879 | 0.82 | SIRT2 (0.52) | SIRT2KDM4EALDH1A1LMNASLC7A5 | |
| SCHEMBL12993003 | 0.81 | SIRT2 (0.49) | SIRT2KDM4EALDH1A1LMNAPTPN1 | |
| SCHEMBL23866994 | 0.81 | CYP4F2 (0.46) | KDM4EALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL5043214 | 0.81 | LOXL2 (0.57) | SIRT2KDM4EALDH1A1LMNASLC7A5 | |
| SCHEMBL7716761 | 0.81 | SIRT2 (0.51) | SIRT2KDM4EALDH1A1LMNASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | UNIV TEXAS (US) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | SIRT2 4498/4885KDM4E 3415/4885ALDH1A1 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.