Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 6/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867522 | 0.88 | HTR2A (0.53) | HTR2AHTR2CDRD3SRC | |
| SCHEMBL23867578 | 0.84 | HTR1A (0.48) | HTR2ADRD3SRC | |
| SCHEMBL23867572 | 0.81 | ACHE (0.48) | HTR2ADRD3SRC | |
| SCHEMBL23867482 | 0.78 | HRH3 (0.52) | HTR2AHTR2CCTNNB1TCF7L2 | |
| SCHEMBL23867574 | 0.76 | PYGM (0.53) | HTR2AHTR2CDRD3SRC | |
| SCHEMBL23867519 | 0.75 | HTR2A (0.51) | HTR2AHTR2CDRD3SRCBRD4 | |
| SCHEMBL23867581 | 0.73 | HTR2A (0.40) | HTR2AHTR2CDRD3 | |
| SCHEMBL23867509 | 0.73 | CCNE1 (0.50) | — | |
| SCHEMBL23867525 | 0.73 | HTR2A (0.49) | HTR2AHTR2CDRD3SRC | |
| SCHEMBL23867521 | 0.72 | HTR1A (0.50) | HTR2AHTR2CDRD3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195279-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-09-30 | — | — | WO | disclosed |