Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723973 | 0.81 | NPSR1 (0.49) | ALDH1A1CES2CES1POLBMEN1 | |
| SCHEMBL462447 | 0.78 | CYP1A2 (0.66) | ALDH1A1CYP1A2LMNAHSD11B1CYP2D6 | |
| SCHEMBL9247708 | 0.78 | SRC (0.56) | ALDH1A1CYP1A2LMNACYP2D6SRC | |
| SCHEMBL7099669 | 0.77 | KMT2A (0.47) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7100498 | 0.77 | MMP8 (0.49) | ALDH1A1LMNACYP2D6CYP2C19MEN1 | |
| SCHEMBL3410010 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2LMNACYP2D6SRC | |
| SCHEMBL156143 | 0.77 | LMNA (0.58) | ALDH1A1CYP1A2LMNACYP2D6SRC | |
| SCHEMBL8916370 | 0.77 | LMNA (0.58) | ALDH1A1CYP1A2LMNACYP2D6SRC | |
| Hydrochloric Acid SCHEMBL3647675 | 0.77 | ALDH1A1 (0.64) | ALDH1A1CYP1A2LMNAHSD11B1CYP2D6 | |
| SCHEMBL13389325 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2LMNACYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326919-B | Phenyl butanone of 5 nitro of compound 2 hydroxyl, 3 fluorine 1 and preparation method thereof and agricultural biological activity | 青岛农业大学 | 2018-01-02 | — | — | CN | claimed |
| US-20210299126-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | BRISTOL-MYERS SQUIBB COMPANY | 2021-09-30 | — | — | US | disclosed |
| CN-107615168-A | Radiation-sensitive composition | 日产化学工业株式会社 | 2018-01-19 | — | — | CN | disclosed |
| CN-104326919-B | Phenyl butanone of 5 nitro of compound 2 hydroxyl, 3 fluorine 1 and preparation method thereof and agricultural biological activity | 青岛农业大学 | 2018-01-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299126-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | IDO1, IDO2, INMT | ALDH1A1 373/4885CYP1A2 89/4885LMNA 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.