Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101663 | 0.88 | LMNA (0.46) | MMP8GAASMN1; SMN2KMT2ALMNA | |
| SCHEMBL7101016 | 0.85 | NPC1 (0.48) | CYP3A4SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL7099669 | 0.85 | KMT2A (0.47) | KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL7101691 | 0.84 | ALDH1A1 (0.46) | CYP2D6SMN1; SMN2KMT2ALMNATSHR | |
| SCHEMBL6432556 | 0.83 | CYP2D6 (0.53) | MMP8CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL5751142 | 0.82 | MMP8 (0.50) | MMP8CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL27557939 | 0.82 | MMP8 (0.50) | MMP8CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL4290959 | 0.81 | MMP8 (0.56) | MMP8CYP3A4CYP2C19GAASMN1; SMN2 | |
| SCHEMBL324209 | 0.81 | MMP8 (0.56) | MMP8CYP3A4CYP2C19GAASMN1; SMN2 | |
| SCHEMBL2400228 | 0.81 | MMP8 (0.56) | MMP8CYP3A4CYP2C19GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |