Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972393 | 0.79 | P2RX7 (0.53) | P2RX7ALDH1A1 | |
| SCHEMBL10242696 | 0.79 | P2RX7 (0.49) | P2RX7ALDH1A1 | |
| SCHEMBL2172793 | 0.79 | P2RX7 (0.49) | P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL14759859 | 0.77 | P2RX7 (0.48) | P2RX7ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1372267 | 0.77 | P2RX7 (0.48) | P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL23869398 | 0.76 | P2RX7 (0.47) | P2RX7ALDH1A1 | |
| SCHEMBL15980738 | 0.74 | CYP1A2 (0.33) | P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL352491 | 0.74 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL18255993 | 0.74 | P2RX7 (0.49) | P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL13235907 | 0.73 | ALDH1A1 (0.42) | P2RX7ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210299126-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | BRISTOL-MYERS SQUIBB COMPANY | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299126-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | IDO1, IDO2, INMT | P2RX7 2683/4885ALDH1A1 373/4885L3MBTL1 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.