Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22543431 | 0.73 | MGLL (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL28931864 | 0.73 | MGLL (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL43850 | 0.72 | SMN1; SMN2 (0.38) | ALDH1A1ALOX12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14325520 | 0.71 | MGLL (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL26177011 | 0.68 | ALDH1A1 (0.39) | ALDH1A1ALOX12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL121100 | 0.68 | TSHR (0.40) | ALDH1A1ALOX12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12023038 | 0.68 | TSHR (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8859577 | 0.67 | RAB9A (0.36) | ALDH1A1ALOX12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5088057 | 0.67 | TSHR (0.37) | ALDH1A1ALOX12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16937301 | 0.66 | MEN1 (0.44) | ALDH1A1ALOX12MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110229556-A1 | LIPID-COATED POLYMER PARTICLES FOR IMMUNE STIMULATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-09-22 | — | — | US | disclosed |