Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274254 | 0.79 | BRD4 (0.38) | BRD4SRD5A1 | |
| SCHEMBL321647 | 0.79 | DRD2 (0.36) | HSD17B1SRD5A1 | |
| SCHEMBL16290456 | 0.78 | HSD17B1 (0.34) | HSD17B1SRD5A1 | |
| SCHEMBL13892590 | 0.76 | ALDH1A1 (0.37) | BRD4SRD5A1PARP10PARP11 | |
| SCHEMBL9016026 | 0.76 | CASP1 (0.37) | BRD4SRD5A1PARP10PARP11 | |
| SCHEMBL30994051 | 0.76 | ACLY (0.45) | HSD17B1 | |
| SCHEMBL5955592 | 0.76 | NOTUM (0.38) | BRD4NOTUMSRD5A1PARP10PARP11 | |
| SCHEMBL1727000 | 0.76 | HSD17B1 (0.33) | HSD17B1SRD5A1PARP10PARP11 | |
| SCHEMBL21098684 | 0.76 | PBRM1 (0.41) | HSD17B1 | |
| SCHEMBL29375857 | 0.76 | HSD17B1 (0.33) | HSD17B1SRD5A1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889138-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2021-10-06 | — | — | EP | disclosed |