Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310539 | 0.75 | SLC6A2 (0.42) | ACHESLC6A2SLC6A4SLC6A3RAB9A | |
| SCHEMBL5537503 | 0.73 | CYP19A1 (0.36) | ACHETDP1KDM1AMAPTHTR2A | |
| SCHEMBL1405569 | 0.70 | ESR2 (0.50) | ACHETDP1MAPTHTR2AHTR2C | |
| SCHEMBL7794528 | 0.70 | ALDH1A1 (0.40) | MAPTCYP19A1KMT2ASLC18A3RAB9A | |
| SCHEMBL38651941 | 0.69 | MAOB (0.39) | ACHEKDM1AMEN1KMT2AALDH1A1 | |
| SCHEMBL2537599 | 0.67 | SLC18A3 (0.52) | ACHETDP1MAPTSLC18A3HTT | |
| SCHEMBL43080 | 0.67 | SLC18A3 (0.56) | ACHETDP1MAPTSLC18A3HTT | |
| SCHEMBL23722780 | 0.66 | KDM1A (0.33) | ACHETDP1KDM1AMAPTHTR2A | |
| SCHEMBL23891752 | 0.65 | PDE5A (0.32) | HTR2AHTR2CHTR2BCYP19A1THRB | |
| SCHEMBL8025878 | 0.65 | LMNA (0.59) | TDP1MAPTKMT2ASLC18A3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916893-B2 | Polymerization-active transition metal complexes having bulky ligand systems | SER. V. GMBH (DE) | 2005-07-12 | — | — | US | claimed |
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | RIEGER BERNHARD (DE) | 2004-09-02 | — | — | US | claimed |
| US-6916893-B2 | Polymerization-active transition metal complexes having bulky ligand systems | SER. V. GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | RIEGER BERNHARD (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171774-A1 | Polymerization-active transition metal complexes having bulky ligand systems | AP1M1, CCNC, CLTB | ACHE 4396/4885TDP1 3418/4885KDM1A 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.