Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | Q9HBH1 | 3/20 | 0.32 | |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788049 | 0.83 | CTSS (0.40) | ALDH1A1CTSSCTSKL3MBTL1MME | |
| SCHEMBL22388824 | 0.81 | CTSS (0.45) | ALDH1A1CTSSCTSKCTSLCTSB | |
| SCHEMBL13596341 | 0.79 | MEN1 (0.42) | ALDH1A1CTSSCTSKCTSLCTSB | |
| SCHEMBL14779115 | 0.78 | CTSK (0.58) | CTSSCTSKPSENEN | |
| SCHEMBL13595467 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CTSSCTSKCTSLCTSB | |
| SCHEMBL19964622 | 0.72 | SIGMAR1 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL22388966 | 0.70 | MMP1 (0.35) | CTSSCTSK | |
| SCHEMBL7405329 | 0.70 | ALDH1A1 (0.37) | ALDH1A1CTSSCTSKCTSLCTSB | |
| SCHEMBL7405326 | 0.70 | ALDH1A1 (0.37) | ALDH1A1CTSSCTSKCTSLCTSB | |
| SCHEMBL31135777 | 0.70 | MMP1 (0.35) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |