Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912627 | 0.83 | MEN1 (0.70) | MEN1KMT2ARECQLMAPTSLC6A5 | |
| SCHEMBL23901259 | 0.82 | ADRA1A (0.58) | KDM4EKDM5AKDM4C | |
| SCHEMBL13226890 | 0.81 | EPHX2 (0.42) | MEN1KMT2AKDM4EDNM1EPHX2 | |
| SCHEMBL45902 | 0.77 | MEN1 (0.74) | MEN1KMT2AKDM4EPLA2G4AEPHX2 | |
| SCHEMBL14003537 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ALMNADNM1ALDH1A1 | |
| SCHEMBL23879339 | 0.76 | PRMT1 (0.36) | LMNAATMKDM5AKDM4C | |
| SCHEMBL8068893 | 0.76 | AKR1B1 (0.60) | MEN1KMT2AALDH1A1KDM5AKDM4C | |
| SCHEMBL19400289 | 0.76 | MEN1 (0.71) | MEN1KMT2APLA2G4AEPHX2ALDH1A1 | |
| SCHEMBL5522638 | 0.76 | MEN1 (0.71) | MEN1KMT2APLA2G4AEPHX2ALDH1A1 | |
| SCHEMBL20009655 | 0.76 | MEN1 (0.71) | MEN1KMT2APLA2G4AEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143678-A | Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |