Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 9/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23894071 | 0.82 | MEN1 (0.53) | KDM4EKDM4CKDM5A | |
| SCHEMBL285421 | 0.82 | ADRA1A (0.83) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| Hydrochloric Acid SCHEMBL11026786 | 0.80 | ADRA1A (0.79) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL23879339 | 0.79 | PRMT1 (0.36) | ADRA1AMAPK1KDM4AKDM4CKDM5A | |
| Phosphoric Acid SCHEMBL8514542 | 0.79 | ADRA1A (0.70) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL20159780 | 0.77 | ZDHHC20 (0.46) | ADRA1AKDM4EMAPK1KDM4AKDM4C | |
| SCHEMBL406942 | 0.76 | KDM4E (0.56) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL1331412 | 0.76 | ADRA1A (0.95) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL27941457 | 0.75 | KDM4E (0.67) | ADRA1AKDM4EMAPK1HIF1AFOLH1 | |
| SCHEMBL8068893 | 0.75 | AKR1B1 (0.60) | KDM4CKDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210308277-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210308277-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | CD2BP2, DCLRE1A, EPCAM | ADRA1A 4644/4885KDM4E 3062/4885MAPK1 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.