Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SPR | P35270 | 4/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901730 | 0.85 | L3MBTL1 (0.49) | L3MBTL1SPRHSP90AA1MAPTTP53 | |
| SCHEMBL23901474 | 0.79 | SPR (0.48) | SPRSCD5RIPK1P2RX7 | |
| SCHEMBL23901647 | 0.70 | AVPR2 (0.42) | L3MBTL1HSP90AA1P2RX7 | |
| SCHEMBL23901483 | 0.68 | USP30 (0.45) | SPRSCD5ALDH1A1P2RX7HPGD | |
| SCHEMBL11613972 | 0.67 | L3MBTL1 (0.51) | L3MBTL1LMNAPOLBALDH1A1TSHR | |
| SCHEMBL23901500 | 0.67 | SPR (0.54) | SPRSCD5TP53 | |
| SCHEMBL18642715 | 0.67 | L3MBTL1 (0.51) | L3MBTL1RIPK1 | |
| Zinc Ion SCHEMBL11709381 | 0.66 | L3MBTL1 (0.50) | L3MBTL1LMNAPOLBALDH1A1TSHR | |
| SCHEMBL425716 | 0.66 | L3MBTL1 (0.42) | L3MBTL1LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL20710310 | 0.66 | RIPK1 (0.63) | L3MBTL1POLBMAPTRIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |