Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901479 | 0.85 | L3MBTL1 (0.51) | L3MBTL1P2RX7HSP90AA1MAPTSPR | |
| SCHEMBL23901483 | 0.80 | USP30 (0.45) | P2RX7RAB9ASPRCNR1 | |
| SCHEMBL23901647 | 0.80 | AVPR2 (0.42) | L3MBTL1P2RX7HSP90AA1 | |
| SCHEMBL4766465 | 0.71 | MAPT (0.61) | L3MBTL1HSP90AA1GAAMAPTSMN1; SMN2 | |
| SCHEMBL22405367 | 0.69 | P2RX7 (0.45) | L3MBTL1P2RX7GAAMAPTRAB9A | |
| SCHEMBL3426843 | 0.68 | HPGD (0.55) | HSP90AA1 | |
| SCHEMBL5663191 | 0.68 | HSD11B1 (0.48) | HSP90AA1HSP90AB1SMN1; SMN2RAB9ACRBN | |
| SCHEMBL11888856 | 0.68 | RAB9A (0.68) | GAAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL7232623 | 0.68 | CYP2C9 (0.73) | SMN1; SMN2SPR | |
| SCHEMBL23901474 | 0.68 | SPR (0.48) | P2RX7SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |