Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21449131 | 0.84 | ALOX12 (0.37) | ALOX12ALOX15GABRA1GABRB2LMNA | |
| SCHEMBL10053122 | 0.82 | L3MBTL1 (0.39) | LMNARNASEH1SLC5A1SLC5A2TRPA1 | |
| SCHEMBL1437611 | 0.80 | SLC5A1 (0.42) | ALOX12LMNARNASEH1SLC5A1SLC5A2 | |
| SCHEMBL20946452 | 0.80 | PNMT (0.43) | ALOX12LMNAPNMTSLC5A1SLC5A2 | |
| SCHEMBL5018843 | 0.79 | SLC6A2 (0.45) | ALOX12ALOX15GABRA1GABRB2LMNA | |
| SCHEMBL11810508 | 0.78 | LMNA (0.35) | ALOX12GABRA1GABRB2LMNARNASEH1 | |
| SCHEMBL10019194 | 0.78 | KCNH2 (0.39) | ALOX12ALOX15GABRA1GABRB2PNMT | |
| SCHEMBL7637108 | 0.78 | GABRA1 (0.60) | ALOX12ALOX15GABRA1GABRB2LMNA | |
| SCHEMBL12016027 | 0.77 | IDO1 (0.40) | LMNASLC5A1SLC5A2TRPA1PTGS1 | |
| SCHEMBL10510199 | 0.77 | HTR1D (0.51) | ALOX12LMNAPNMTSLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021203016-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | WO | disclosed |