Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958594 | 0.88 | CCR1 (0.44) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL23905909 | 0.80 | ALDH1A1 (0.50) | CCR1CCR5CCR8PRNPNPSR1 | |
| SCHEMBL30007139 | 0.78 | KMO (0.40) | CCR1CCR5CCR8KDM4EKMO | |
| SCHEMBL23196004 | 0.78 | KMO (0.40) | CCR1CCR5CCR8KDM4EKMO | |
| SCHEMBL23905520 | 0.78 | CCR1 (0.41) | CCR1CCR5CCR8PRNPNPSR1 | |
| SCHEMBL23905332 | 0.77 | SYK (0.37) | CCR1CCR5CCR8PIK3CAPIK3R1 | |
| SCHEMBL30211305 | 0.77 | PARP1 (0.43) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL23905323 | 0.77 | SYK (0.36) | CCR1CCR5CCR8PIK3CAPIK3R1 | |
| SCHEMBL25687961 | 0.76 | ATM (0.41) | ALDH1A1KDM4EPSMD14KMO | |
| SCHEMBL23905483 | 0.75 | CA12 (0.39) | ALDH1A1MAPTKDM4EPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |