Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958594 | 0.85 | CCR1 (0.44) | SYKPIK3CAPIK3R1CCR1CCR5 | |
| SCHEMBL23905323 | 0.83 | SYK (0.36) | SYKPIK3CAPIK3R1CCR1CCR5 | |
| SCHEMBL23958607 | 0.82 | ACHE (0.36) | CCR1CCR5CCR8PDGFRBPDGFRA | |
| SCHEMBL23905317 | 0.80 | KDM4E (0.38) | PIK3CAPDGFRBPDGFRA | |
| SCHEMBL23904848 | 0.79 | KMO (0.37) | KMO | |
| SCHEMBL23905484 | 0.77 | CCR1 (0.40) | SYKPIK3CAPIK3R1CCR1CCR5 | |
| SCHEMBL30007139 | 0.70 | KMO (0.40) | CCR1CCR5CCR8KMO | |
| SCHEMBL23196004 | 0.70 | KMO (0.40) | CCR1CCR5CCR8KMO | |
| SCHEMBL23905312 | 0.70 | MCHR1 (0.39) | SYKCCR1CCR5CCR8 | |
| SCHEMBL30211305 | 0.69 | PARP1 (0.43) | CCR1CCR5CCR8KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |