Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 20/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620722 | 0.83 | LMNA (0.44) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23195592 | 0.83 | LMNA (0.44) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23195925 | 0.82 | HTT (0.51) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23905397 | 0.81 | HPGDS (0.51) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23166684 | 0.80 | HRH1 (0.45) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL23196051 | 0.76 | HTR1A (0.42) | HRH1KCNH2CYP3A4CYP2D6CHRM1 | |
| SCHEMBL24345422 | 0.76 | HRH1 (0.44) | HRH1KCNH2 | |
| SCHEMBL23195601 | 0.74 | CCR1 (0.49) | CYP3A4CYP2D6CHRM1 | |
| SCHEMBL29506919 | 0.74 | DDB1 (0.56) | CYP3A4CYP2D6 | |
| SCHEMBL22428729 | 0.73 | HRH1 (0.48) | HRH1KCNH2CYP3A4CYP2D6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |