Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR6 | O00574 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24363611 | 0.85 | POLB (0.38) | LMNATP53POLBKMT2A | |
| SCHEMBL24345454 | 0.85 | POLB (0.38) | LMNATP53POLBKMT2A | |
| SCHEMBL23905661 | 0.85 | LMNA (0.33) | LMNATP53POLBKMT2A | |
| SCHEMBL23904817 | 0.82 | LRRK2 (0.34) | LMNATP53 | |
| SCHEMBL24363581 | 0.82 | SLC5A7 (0.38) | KMT2A | |
| SCHEMBL23905470 | 0.80 | — | — | |
| SCHEMBL23905459 | 0.79 | POLB (0.36) | LMNAPOLBKMT2AROCK2ROCK1 | |
| SCHEMBL23905666 | 0.79 | ROCK2 (0.33) | POLBROCK2ROCK1 | |
| SCHEMBL23905701 | 0.78 | AR (0.35) | POLB | |
| SCHEMBL23195596 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |