Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGFR | P43088 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24345454 | 0.87 | POLB (0.38) | LMNATP53ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL24363611 | 0.87 | POLB (0.38) | LMNATP53ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL23904817 | 0.86 | LRRK2 (0.34) | LMNATP53GABRA5 | |
| SCHEMBL23905469 | 0.85 | CXCR6 (0.32) | LMNATP53POLBKMT2A | |
| SCHEMBL24363581 | 0.84 | SLC5A7 (0.38) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23905547 | 0.84 | LMNA (0.32) | LMNATP53ALDH1A1SMN1; SMN2PTGFR | |
| SCHEMBL23905636 | 0.84 | POLB (0.33) | LMNATP53ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL23905464 | 0.83 | ROCK2 (0.33) | MAPT | |
| SCHEMBL23905558 | 0.83 | GABRA5 (0.31) | LMNATP53GABRA5 | |
| SCHEMBL23905945 | 0.82 | PTGFR (0.32) | LMNATP53POLBKMT2APTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |