Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 7/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905909 | 0.81 | ALDH1A1 (0.50) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL25113804 | 0.81 | CCR1 (0.40) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL26577806 | 0.79 | CCR1 (0.39) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL23905484 | 0.78 | CCR1 (0.40) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL23905544 | 0.77 | HCAR2 (0.37) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL26762014 | 0.77 | RXRA (0.33) | RXRAGRIN1GRIN2B | |
| SCHEMBL23905543 | 0.75 | ATM (0.42) | CCR1CCR5CCR8PSMD14ALDH1A1 | |
| SCHEMBL20351059 | 0.71 | PIK3CA (0.39) | PRNPNPSR1ALDH1A1MAPTRXFP1 | |
| SCHEMBL23905532 | 0.70 | KDM4E (0.56) | CCR1CCR5CCR8PSMD14COPS5 | |
| SCHEMBL21585394 | 0.70 | RXRA (0.38) | RXRAGRIN1GRIN2BMBOAT4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |