Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905365 | 0.81 | CES2 (0.40) | ALDH1A1LMNACES2CES1PTPN1 | |
| SCHEMBL23904744 | 0.79 | CES2 (0.38) | ALDH1A1HPGDLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL18944664 | 0.71 | ATM (0.42) | ALDH1A1LMNAHTR7PTBP1SMN1; SMN2 | |
| SCHEMBL1237696 | 0.68 | TRPA1 (0.44) | ALDH1A1HPGDLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL1237695 | 0.68 | TRPA1 (0.44) | ALDH1A1HPGDLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL24359428 | 0.67 | POLB (0.44) | ALDH1A1HPGDLMNASMN1; SMN2GAA | |
| SCHEMBL23904715 | 0.67 | MAOA (0.38) | LMNAHTR7PTBP1SMN1; SMN2GAA | |
| SCHEMBL29077329 | 0.66 | CES2 (0.52) | ALDH1A1HPGDHTR7SMN1; SMN2ADRB2 | |
| SCHEMBL4869727 | 0.66 | CES2 (0.52) | ALDH1A1HPGDHTR7SMN1; SMN2ADRB2 | |
| SCHEMBL12154075 | 0.66 | ALDH1A1 (0.38) | ALDH1A1HPGDLMNAHTR7PTBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |