Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134591 | 0.81 | PLA2G10 (0.83) | PLA2G10PLA2G2ACYP17A1KMT2APARP10 | |
| SCHEMBL12663746 | 0.80 | PLA2G10 (0.68) | PLA2G10PLA2G2ACYP17A1KMT2APARP10 | |
| SCHEMBL7257033 | 0.76 | ADAM17 (0.55) | PLA2G10PLA2G2ACHEK2 | |
| SCHEMBL1179736 | 0.75 | POLB (0.50) | KMT2AIKBKBHTTLMNA | |
| SCHEMBL28213060 | 0.74 | CYP17A1 (0.49) | PLA2G10PLA2G2ACYP17A1PARP10BRD4 | |
| SCHEMBL23905177 | 0.74 | CYP17A1 (0.89) | PLA2G10PLA2G2ACYP17A1GRM2KMT2A | |
| SCHEMBL13008173 | 0.74 | LMNA (0.40) | KMT2AHTTLMNA | |
| SCHEMBL1719129 | 0.74 | PLA2G2A (1.00) | PLA2G10PLA2G2ACYP17A1KMT2APARP10 | |
| SCHEMBL6490228 | 0.73 | CYP2A6 (0.45) | GRM2KMT2ALMNABRD4 | |
| SCHEMBL6070478 | 0.72 | TUBB4A (0.56) | PLA2G10PLA2G2ACYP17A1KMT2APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |