SCHEMBL23906717

SCHEMBL23906717

CCc1cc2c(N)ncnc2n1C1OC(COCN)C(O)C1O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ HSPA5 P11021 6/20 0.48
▸ ADK P55263 3/20 0.46
▸ ATG7 O95352 3/20 0.45
▸ HSPA8 P11142 2/20 0.45
▸ AMD1 P17707 2/20 0.45
▸ RXFP1 Q9HBX9 1/20 0.45
▸ METTL3 Q86U44 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18464362 0.77 ADK (0.57) HSPA5ADKATG7HSPA8AMD1
SCHEMBL15746955 0.76 HSPA5 (0.45) HSPA5ATG7HSPA8RXFP1METTL3
SCHEMBL19007434 0.75 HSPA5 (0.46) HSPA5ATG7HSPA8RXFP1
SCHEMBL6380760 0.73 HSPA8 (0.61) HSPA5ADKHSPA8RXFP1
SCHEMBL20419330 0.72 HSPA8 (0.58) HSPA5HSPA8RXFP1
SCHEMBL20419169 0.72 HSPA8 (0.58) HSPA5HSPA8RXFP1
SCHEMBL1740449 0.72 HSPA5 (0.63) HSPA5ADKHSPA8RXFP1
SCHEMBL18464494 0.71 ADK (0.51) HSPA5ADKATG7HSPA8RXFP1
SCHEMBL20419157 0.70 HSPA5 (0.61) HSPA5ADKHSPA8RXFP1
SCHEMBL16366344 0.70 HSPA5 (0.60) HSPA5HSPA8AMD1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210308283-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF MODERNA THERAPEUTICS, INC. 2021-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210308283-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF ADAR, NT5C3B, NSUN2 HSPA5 2318/4885ADK 76/4885ATG7 3303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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