SCHEMBL239073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9024796	0.82	LATS1 (0.39)	ALDH1A1MAPTTDP1LMNAMAPK1
	SCHEMBL12403858	0.79	HTT (0.46)	ALDH1A1MAPTTDP1MEN1KMT2A
	SCHEMBL12883442	0.78	RAPGEF4 (0.39)	IDO1MAPK1KDM4EMEN1KMT2A
	SCHEMBL5515933	0.77	PRKCI (0.37)	ALDH1A1MAPTTDP1LMNAMAPK1
	SCHEMBL1662774	0.76	MAPK14 (0.41)	ALDH1A1MAPTTDP1LMNAMAPK1
	SCHEMBL12883439	0.76	LMNA (0.42)	ALDH1A1MAPTLMNAKDM4EMEN1
	SCHEMBL12883490	0.76	KMT2A (0.44)	ALDH1A1MAPTTDP1LMNAMEN1
	SCHEMBL21779243	0.76	MAP2K1 (0.43)	IDO1
	SCHEMBL19194233	0.76	GAA (0.43)	IDO1ALDH1A1MAPTTDP1LMNA
	SCHEMBL9750979	0.73	ALDH1A1 (0.48)	ALDH1A1MAPTLMNAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.